New antiepileptic agents.
نویسندگان
چکیده
Recent US Food and Drug Administration approval of new antiepileptic drugs (AEDs) offers a significant improvement in the treatment of childhood epilepsy. After a period of many years, during which no new AEDs became available, 7 new AEDs were introduced in the United States beginning in 1993. Approximately 25% of pediatric patients who remain refractory to therapy with conventional epileptic drugs now have the availability of more successful outcomes with several new drugs. These new drugs include felbamate, gabapentin, lamotrigine, topiramate, tiagabine, vigabatrin, oxcarbazepine. Information regarding the efficacy of these AEDs, as well as their side effects in the pediatric population has been summarized as an update for the pediatric dentist.
منابع مشابه
Newest Targets for Anticonvulsant Agents: An Overview
Epilepsy is a neurological condition characterized by recurrent seizures influencing about 1% of the worldwide population. Despite much progress in understanding the pathogenesis of epilepsy, the molecular basis of human epilepsy still remains unclear. Common approaches for pharmacotherapy of epilepsy are still directed towards controlling the symptoms and suppression of seizures. Clinical use ...
متن کاملThe new antiepileptic drugs: clinical applications.
In the past decade, 8 new antiepileptic drugs have been approved for use in the United States, offering many new treatment options to patients with epilepsy. With expanding use of these newer agents, primary care clinicians are challenged with understanding the roles that each new agent plays in the treatment of patients with epilepsy as well as possible interactions with other pharmacological ...
متن کاملP 146: The Best New Antiepileptic Drugs to Prevent Orofacial Malformations as Side Effects of Antiepileptic Drugs
Mothers exposed to Antiepileptic drugs (AEDs) are at high risk to born babies with orofacial malformations such as cleft lips. About 9 percent of congenital abnormalities in babies of mothers with epilepsy relates to orofacial abnormalities. Maintaining safe antiepileptic drugs for millions of mothers with epilepsy is very important. Researches show that new AEDs have less side effects than the...
متن کاملEfficacy and tolerability of the new antiepileptic drugs I: Treatment of new onset epilepsy
Objective: To assess the evidence demonstrating efficacy, tolerability, and safety of seven new antiepileptic drugs (AEDs) (gabapentin, lamotrigine, topiramate, tiagabine, oxcarbazepine, levetiracetam, and zonisamide—reviewed in the order in which these agents received approval by the US Food and Drug Administration) in the treatment of children and adults with newly diagnosed partial and gener...
متن کاملAntiepileptic Drugs Combination Therapy And Interactions
antiepileptic drugs combination therapy and interactions antiepileptic drugs combination therapy and interactions this page intentionally left blank chuyên khoa than antiepileptic drugs combination therapy and interactions josé e. cavazos, md phd san antonio va epilepsy center of 40 combination therapy in epilepsy : what, when, how and the importance of drug interactions in epilepsy therapy dru...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Pediatric dentistry
دوره 26 1 شماره
صفحات -
تاریخ انتشار 2004